I love the keyboard.
Yes its capable of doing macros but I have never bothered to program it in. I think it would be hella useful though in games like EVE or Sins etc. Where menus can have some depth to them.
If you look close the red keys say WASD on them along with Q and E above and to the left/right.
The way the other keys are moved away from the movement keys makes them easy to use and your fingers dont slip off. Also you can see the other keys around the movement keys are round giving them a different feel.
I use WASD for movement. F for quick switching. Q for weapon 1. E for weapon 2.
Mouse 4 works awsome for pulling out the shovel real quick. "Use" has always been mouse wheel button for me. With mouse wheel still changing weapons up and down.
Now that I'm thinking about it I really dont think I use mouse 2. Thats really wierd. Used to be my grenade button where you could "milk" the nades and toss em at the right moment.
As for speed with fingers... I have 17 years of guitar and my mind just kinda "plays" without much thought be it Games or Music.